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Cancer Nexus Blog

Read up on the Center's latest developments in cancer research, screening and prevention, as well as innovations in cancer detection and treatment.

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    It’s All about the Gaps: Why Chemotherapy Works on Some Cells but Not Others

    Sharon Cantor, PhD, explains why chemotherapy for hereditary breast and ovarian cancer doesn't always work as expected.

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    A Translational Approach to T cells: A Conversation with Jillian Richmond, PhD

    Jillian Richmond, PhD, discusses her T cell research and its application to diagnostics and therapies for lymphoma.

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    UMass Chan is attending major cancer conference to share advances in cancer research

    Follow Our Research Presentations at the AACR Annual Meeting 2022

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    Simulated Emergencies to the Rescue

    UMass thoracic surgeons perform simulated surgery using a robotic platform to train for an emergency conversion to an open procedure.

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    Paving the Path for Neuro-Oncology Translational Research: A Conversation with David Cachia, MD

    David Cachia, MD talks about future neuro-oncology clinical trials at UMass Chan

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    Adapt2YourMood: A Mood-tailored Intervention for Smoking Cessation

    A pilot study to develop new bioinformatic tools to identify fusion circRNAs in cancer has received funding from the UMass Cancer Center and PQHS

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    Using Single-Cell Profiling to Uncover Vulnerabilities in Breast Cancer

    A study on the epigenetic vulnerabilities of metastatic breast cancer has received funding from the UMass Cancer Center

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    A Dual Approach to Activate the Immune System in Pancreatic Cancer

    A pilot study to develop a unique approach to enhance immunotherapy for pancreatic cancer has received funding from the UMass Cancer Center

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    AIMing to Improve the Response of Melanoma to Immunotherapy

    An early-stage research study of immunotherapy in melanoma has received funding from the UMass Cancer Center

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    Developing Computational Methods to Detect Fusion Circular RNAs in Cancer

    UMass Cancer Center and PQHS fund a pilot study to develop new bioinformatic tools to identify fusion circRNAs in cancer

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    UMass CRO Receives Recognition for Outstanding Performance

    The UMass Cancer Research Office has received national recognition from ECOG-ACRIN for outstanding performance in clinical trials research

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    New Research Sheds Light on Treatment for TP53-Mutant Blood Cancers

    Dr. Patel discusses his new research defining the clinico-genomic landscape of TP53 mutations in patients with AML

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    Using Comparative Genomics to Fight Cancer in Dogs and Humans

    By studying cancer in dogs, researchers at UMass Cancer Center are working to improve the outcomes and extend the lives of both human patients and pet dogs with cancer

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    UMass Selected as Clinical Trial Site for New Experimental Cancer Drug

    UMass was selected as one of only a few sites around North America offering a phase I/II clinical trial involving intratumoral injection

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    Leveraging mHealth to Increase Physical Activity in Cancer Survivors

    Aiming to provide direct link between providers and physical activity programs to conduct patient referrals

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    Combating drug resistance in melanoma

    Ceol 's lab have developed a drug that targets this factor and is currently testing whether it can combat drug resistance when used in combination with current therapies.

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    Teaming Up to Find New Ways to Treat Melanoma

    UMass Cancer Center researchers are developing new therapeutic treatments for melanoma that can be used alone or in combination with current therapies

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    Innovative eHealth System Powered by Collective Intelligence Technology

    Personalized digital technology to address smoking-related health disparities developed by UMass Cancer Center researcher

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    Advancing Lung Cancer Therapy Using Genetic Tools

    Our studies have discovered that the genome (DNA) editing tool known as CRISPR-Cas9 can efficiently induce somatic genome editing in the lungs of adult animals. We designed various delivery vectors that could effectively deliver CRISPR editing components.

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    Cancer Prevention and Control Research at UMass Cancer Center

    Cancer Population Health Sciences research program investigates multi-level factors of cancer risk and treatment outcomes to implement effective cancer screening, prevention, and treatment

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    Paving the way for targeted cancer therapeutics

    We hope to understand how to develop targeted therapies that are effective at suppressing tumor formation in neurofibromatosis type 1, through work in various model systems.

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    COVID-19 Impact on Cancer Survivors' Physical Activity & Mental Health

    Study reveals digital physical activity and mental health support programs may help address ongoing needs of cancer survivors during and after the COVID-19 pandemic

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    UMass Cancer Center is One of Two Sites in Massachusetts Offering a Study of Maintenance Immunotherapy for Throat Cancer

    A Phase II/III Randomized Study of Maintenance Nivolumab Versus Observation in Patients With Locally Advanced, Intermediate Risk HPV-Positive OPSCC

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    Chromosome Biology and its Role in Genome Stability and Carcinogenesis

    In earlier studies, we discovered that a human protein important for duplicating chromosomes also governs the three-dimensional localization of multiple proteins.

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    Promoting Patient–Provider Conversations About Lung Cancer Screening, During the Surge of Covid

    We have been working on a pilot research study that uses technology to facilitate effective communication between patients and healthcare providers about lung cancer screening.

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